Rolandic Epilepsy and the Spectrum of Idiopathic Focal Epilepsies in Children

سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 330

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شناسه ملی سند علمی:

EPILEPSEMED16_017

تاریخ نمایه سازی: 28 بهمن 1398

چکیده مقاله:

Rolandic epilepsy and spectrum of idiopathic focal epilepsies account for 10% to 20% of epilepsies in children. These epilepsies have a number of common features. They are age dependent. Patients have normal neurologic examination and developmental status. Neuroimaging is usually normal. These epilepsies have characteristic EEG findings with spikes of distinctive morphology and variable location superimposed on a normal background. All of these epilepsies have genetic predisposition and have specific seizure semiology. Almost all of these epilepsies rapidly respond to treatments and the prognosis is usually good. However, many issues exist around the treatment of these epilepsies because atypical and extreme forms of Rolandic epilepsy such as Landau Kleffner and Continuous spikes and waves during sleep usually could see after treatment with traditional anti-seizure medications. A number of investigators argue the treatment of these epilepsies with anti-seizures medication such as carbamazepine. These investigators believe that treating many of these patients with Rolandic epilepsy and its spectrum could have deteriorating effects on the EEG during NREM sleep and even could deteriorate cognitive function in these children. They believe that many of these children do not need to treat at all, however, if we need to treat them we need to administer anti-seizure medications without deteriorating effects on EEG and cognition. As a practitioner dealing with children with Rolandic epilepsy, we need to know this spectrum of epilepsies enough and update our knowledge about their treatment.

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نویسندگان

Reza Azizi Mal Amiri

assistant professor Child neurologist, epileptologist, and clinical neurophysiologist, Department of Paediatric Neurology, Golestan Medical, Educational, and Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IRAN