Title: Percutaneous Nephrolithotomy Versus open surgery Surgery: A systematic review of randomized clinical trial

Background: Staghorn stones still represent an intractable challenge to urologists. Open surgery (OS) was once considered to be the gold standard for the surgical treatment of staghorn calculi. Today recent advances in technology have led to the implementation of mini– and micro–percutaneous nephrolithotomy (PCNL) as well as open surgery. This meta-analysis, reviews all study about Nephrolithiasis and two methods ,this advantage and complications. Search Method: The relevant empirical literature was identified by searching several electronic databases: PubMed and NLM Gateway (for MEDLINE), Institute of Scientific Information (ISI), SCOPUS and EMBASE , between January 1991 to May 2019 The search was performed by cross-referencing the words Percutaneous Nephrolithotomy , PCNL, Renal stones, minimally invasive percutaneous procedures or etc . The analyses were conducted with SPSS software, version 23.0. Result : The reported prevalence is presented as percent and 95% confidence interval. he search yielded 38 publications that were related to inclusion criteria. According to titles, 20publications were excluded as clearly ineligible, leaving 8 for further review. Of these 18 studies, 8 had been reported that PCNL had significant beneficial effect in prevention of Surgical site infections following surgical procedure but no significant difference between in primary outcome Conclusion: The pooled data showed that there was no significant difference between PCNL and OS, while PCNL provided a significantly lower immediate- stones free rate compared with OS. PCNL provided significantly lower overall complication rate compared with OS. However, no significant differences were found in minor complications and major complications. PCNL provided significantly shorter operative times and hospitalization times compared with OS. And PCNL provided significantly less blood loss and blood transfusion compared with OS .

کلیدواژه ها:

PCNL ، Renal stones. Miniperc