Green synthesis, characterization and antibacterial activities of Silver nanoparticles using Crataegus pentagyna leaf extract

سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 287

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شناسه ملی سند علمی:

SRMMED22_418

تاریخ نمایه سازی: 19 آبان 1398

چکیده مقاله:

Background and Objective: Noble metal nanoparticles are become increasingly popular, especially owing to their excellent biocompatibility. Silver nanoparticles are considerable on of the most widely used metallic nanoparticles because of their physicochemical properties and broad antibacterial activities against both gram-negative and gram-positive bacteria which have raised much concern in the biomedical fields. This paper describes a rapid and eco-friendly method for green synthesis of silver nanoparticles using Crataegus pentagyna leaf extract. Materials and Methods: Green synthesis of silver nanoparticles (Ag NPs) from aqueous solution of silver nitrate by using Crataegus pentagyna leaf extract as a reducing agent has been reported in the present study. The characteristics of the Ag NPs were investigated using techniques: XRD, TEM, FE-SEM, EDS and FT-IR spectroscopy. In addition, the antibacterial activity of synthesized silver nanoparticles against different bacterial strains (such as Escherichia coli, Acinetobacter, Staphylococcus aureus and Proteus) was evaluated by minimal inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) methods. Findings:The FE-SEM images showed that the nanoparticles had a spherical shape and the mean diameter of them was about 35-45 nm. The obtained XRD and EDS results demonstrated that pure cubic Ag NPs were successfully synthesized via co-precipitation method. As well as, the results confirmed that the Crataegus pentagyna is a good eco-friendly and nontoxic source for the synthesis of silver nanoparticles as compared to the conventional chemical/physical routs. Conclusion: In this study, we have demonstrated an eco-friendly, rapid green chemistry method for the synthesis of Ag NPs by using Crataegus pentagyna, which provides a simple, cost effective and efficiency way for synthesis of silver nanoparticles. Further, these prepared nanoparticles have high antibacterial activity.

نویسندگان

Mina Shirzadi-Ahoodashti

Student Research Committee, Department of Medicinal Chemistry, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran

Sobhan Mortazavi-Derazkola

Pharmaceutical Sciences Research Center, Hemoglobinopathy Institute and Department of Medicinal Chemistry, School of Pharmacy, Mazandaran University of Medical Science, Sari, Iran.

Mohammad Ali Ebrahimzadeh

Pharmaceutical Sciences Research Center, Hemoglobinopathy Institute and Department of Medicinal Chemistry, School of Pharmacy, Mazandaran University of Medical Science, Sari, Iran.