Identification of the types and antibiotic-resistance patterns of urinary-tract infection bacteria in razi Qaemshar hospital

Background and purpose: Urinary-tract infection is one of the most common bacterial infection that threaten human health. Increased drug resistance in this bacteria, make it essential to determine the antibiotic-resistance patterns for a better treatment. Current research is focused on identifying the types and antibiotic-resistance patterns of bacteria caused urinary tract infection. Materials and methods: In this investigation, bacteria were isolated from urine samples of the patients referred to razi hospital in qaemshahr, Iran, during Characterization and typing of the isolates performed based on biochemical and microbiological methods. Antibiotic-resistance patterns was evaluated using the disk diffusion method in Mueller Hinton agar medium based on instruction of (Clinical and Laboratory Standards Institute), The data were analyzed by software spss18. Results: of 1338 Bactria isolated from urine samples912 of them were Escherichia coli(68%), and the rest were, 117 isolates citrobacter (9%), 84 isolates entrobacter (6%), 80 isolates pseudomonas anriginousa (6%), 55 isolates enterococcus( 4%), 65 isolates staphylococcus saprophyticus (5%), 25 isolates proteus (2%). The highest antibiotic resistance was observed toward nalidixic acid (68/08%), cotrimoxazole (66/36%), amikacin (64/48%) ،and ampicillin (57/92%). Also the lowest resistant were toward nitrofurantoin85/65% and ceftriaxone60/61%. Conclusions: Our results showed that Escherichia coli is the most prevalent cause of urinary-tract infection in studied patients. Also, regarding to high resistance of the isolates toward nalidixic acid, cotrimoxazole, ampicillin and amikacin, the antibiotic should not be applied in initial treatment of urinary infection.

کلیدواژه ها:

Urinary-tract infection ، Antibiotic resistance ، bacterial agents