Patient and physician preferences for type 2 diabetes medications using discrete-choice method: a systematic review

Background and Objective: There are several therapies for treating type 2 diabetes (T2D). Each of these treatments has certain characteristics. For this reason, T2D patients and specialists have different preferences and select power. Therefore, we did this systematic study in order to extract attributes of anti-diabetic medications, and patients preferences and physicians preferences for type 2 diabetes medications. Search Method: We searched the PubMed, Ovid, Web of science, Scopus, and Embase databases for articles have been published on or before May 2018. In this systematic review, We used following terms: preferences, stated preference, patient preference, patient preferences, physician preferences, physician preference, choice modeling, discrete choice, choice experiment, discrete choice experiment, contingent valuation, and type 2 diabetes. Findings: The searches identified 3346 studies, of which 17 were included in the final synthesis and 27 attributes of type 2 anti-diabetic have been investigated. The most important attributes are changes of blood glucose and HbA1c level, hypoglycemia events, weight changes, gastrointestinal complications, cardiovascular effects, drug cost, and administration mode and dosage of drugs. Conclusion: physicians and patients prefer antidiabetics that be reducing blood glucose and HbA1c level effectively, in addition to, those have low side effects (hypoglycemic event, cardiovascular and gastrointestinal), the effect of weight reduction, low cost, low dosing and low frequency of using. Health care providers and Specialist should consider to these attributes in treatment process.

کلیدواژه ها:

preference(s) ، type 2 diabetes ، anti-diabetic ، systematic review.