An investigation of Neonatal mortality and its Main Determinants in Late Preterm Infant, Hamadan, Iran. 2014-15

Objectives: Late preterm infants are born at a gestational age between 34+1 and 36+6 weeks, they have higher morbidity and mortality rates than term infants (gestational age ≥37 weeks). The aim of this study was to determine mortality rate and its main indicators in these infants. Materials and Methods: In this retrospective, cross-sectional study the medical records of late preterm infant hospitalized in Fatemieh hospital of Hamadan were extracted during one-year period (2014 – 2015). Demographic information including sex, birth weight, causes of hospitalization and complications of disease, length of stay, and outcome were assessed. The collected data were analyzed with SPSS 18 software. Results: Out of 150 infants studied in this research, 52% were female and 48% were male. Mean weight was 2775±572 grams. Mean admission days was 9.1±4.7 days. Respiratory distress syndrome(RDS) was the most common cause of admission were (80/7%). Neonatal mortality rate was overall 7/3% According to logistic regression, need for resuscitation and ventilation, CNS involvement (seizure) (P < 0.001), congenital heart disease (P < 0.001), need to surfactant administration (P = 0.034), pneumonia (P = 0.018), Feeding problems (P < 0.001), Hypoglycemia (P = 0.048) and Septicemia (P < 0.001). could all strongly predict occurrence of death in late-preterm infants.Conclusion: Neonatal mortality is high in late preterm infants and can be predicted by need to intensive supports for respiratory distress syndrome, CNS involvement, congenital heart disease and Septicemia.

کلیدواژه ها:

late preterm ، mortality ، risk factors ، outcome.