Reduction of Hospital Infectious Disposal Wastes by Production of a Biocompatible and Antibacterial Wound Dressing

The aim of this study is to synthesize a biocompatible and antibacterial nanofiber wound dressing Containing Gelatin and Thyme essential oil as antibacterial agent by electrospinning technique. Gelatin has a potential capability in migration of fibroblast cells and growth factors to the wound area and Thyme essential oil take an important role in strengthening antibacterial activity of wound dressing. As a result the nanofiber obtained will accelerate the healing of wounds and during the healing process the less amount of Hospital disposal wastes are produced. On the other hand traditional wound dressings take long time for wound healing and a large amount of hospital infectious wastes are produced. To do this, solutions with different ratio of Cellulose Acetate to Gelatin were prepared to achieve smooth and beadless fibers with small diameter of fibers and a porous structure. Regarding the above mentioned factors the best ratio was chosen and invitro analysis was taken out. The invitro evaluation tests showed that this new wound dressing would be a promising candidate as an effective wound dressing by having a considerable effect on healing of wounds. So by using these wound dressing a large amount of hospital infectious wastes containing disposed wound dressings can be reduced and it also decreases the cost and time of wound healing process.