Investigating the Direct and Indirect Impacts of MS on Body Structure and How It Affects the Quality of Life of Patients in Isfahan Province

Multiple Sclerosis (MS) is an unpredictable degenerative disorder which affects the central nervous system (CNS), specifically the brainand the spinal cord. It involves damages to the fatty myelin sheaths that its task is to protect the nerve fibers and promotes the transmission of nerve impulses symptoms. MS vary widely from person to person and may include sensory disturbances in the limbs, problems with muscle control, tremors muscle stiffness, hyperreflexia, weakness, difficultly walking, poor bladder control and vision problems. Therefore, thisstudy was conducted to investigate and understand the symptoms and complications of the disease in patients with MS. Materials and Methods: This descriptive study was performed on 50 patients among members of the MS society of Isfahan that were selected randomlyby convenience sampling. Demographic information including age, gender, marital status and taking the drugs were evaluated. The data collection tools were questioners (MSQOL-54, MSIS-29). The data was analyzed by the software of the statistical community(SPSS, Minitab) after collecting. Results: After data analyzing the results showed that 40.6 percent of patients suffered from relapsing-remitting multiple sclerosis. 31.2percent under 5 years 45.7percent between 5-10 years and 25.7percent over 10 years, hadMS history. Also frequency of patients’ hospitalization was 21.6percent once, 10percent twice, and 37.5percent more than twice. The most common symptoms were 70percent fatigue and weakness, 65percent balance impairment, 55.7percent poor bladder control, 30percentsleep disorder which considered in the progression of the disease in the first and the second year. Conclusion: MS is an autoimmune central nervous system that the most patients are women with ages between 20-40. This disease affects the life quality of patients by slow downor blocking messages between the brain and body.