Effect of Royal Jelly in The Presence of Folic Acid Supplement on NMRI Mouse Sperm Count

Background: About 40 percent of infertility factors are related to men, which can affect a person s job, body, personality, and mentality. Royal jelly is a protein secretion from the Hypophar-ynx and the lower jaw glands of the worker bee. Only the food given to it during the lifetime of the queen bee and all the small larvae are fed with royal jelly. Extensive combinations of it, as well as many properties like the antioxidant properties of this material have been proven. That s why we chose this material to measure its effects on the sperm count, as well as in the pres-ence of Folic acid supplementation, which is important in the quality of male fertility.Materials and Methods: In this study, NMRI mouse weighing approximately 20 grams were used. Royal jelly at doses of 0.1, 0.2 mg/Kg and Folic acid, at doses of 0.08, 0.15 mg/Kg was injected intraperitoneally for 15 days. The cauda epididymis was removed by surgery and transferred to MHRM medium and studied after incubation.Results: The results showed that the sperm count in the Royal jelly (0.1 mg/kg) and Folic acid groups (0.08 mg/kg) signifi-cantly increased compared to the control group. Other groups did not increase significantly.Conclusion: According to the results of this study, Royal jelly has increased the sperm count, and the use of Folic acid as a supplement to it further increases the sperm count and male fer-tility. The results of this study can be used in the pharmaceutical industry to produce drugs to improve male fertility.

کلیدواژه ها:

Royal Jelly ، Folic Acid ، Sperm Count ، Sperm Quality