Reproductive Outcome in Infertile Men with Acephalic Spermatozoa Syndrome Referring to Royan Institute

Background: Male infertility problems may be contribu-tory to 30- 40% of infertile couples. Teratozoospermia is one of the main causes of male infertility. Acephalic spermatozoa syndrome is an apparently rare and severe type of teratozoo-spermia, and it is characterized by a predominance of headless spermatozoa. ART seems to be the main treatment for these pa-tients to dominate infertility.The purpose of current study was evaluating the ART outcome in infertile men with acephalic spermatozoa syndrome referring to Royan institute.Materials and Methods: To this end, we undertook a complete review of the available data on the ART outcomes of 18 infer-tile couples. We retrospectively evaluated the ART outcomes of patients with 25-90% acephalic spermatozoa. Semen analysis done based on WHO guidelines.Results: From a total number of 18 couples, 9 couples un-derwent ART (2 IVF and 18 ICSI cycles). 135 oocytes, 91 in-jected oocytes and 24 embryo transfers (ETs) were included in the analysis representing. From these 20 cycles, in 5 cycles, oocytes were frozen, in one case, no embryo was formed. To-tally, one pregnancy achieved (from a case with 36 % acephalic sperm) resulted to one healthy boy.Conclusion: In conclusion, with the emergence of ICSI, births were possible, although results are still not completely satisfac-tory. Pregnancy rate with ICSI was low but when pregnancy occurred, embryonic development happened properly and led to the birth of a healthy baby. This study can be a hopeful plan in reproductive medicine to treatment patients with acephalic spermatozoa syndrome.

کلیدواژه ها:

Acephalic Spermatozoa Ayndrome ، ART ، Male Infer-tility