as a readily available and efficient catalyst promoted ginelli synthesis of 3,4-dihydropyrimidin-2-(1H)-one/thione derivatives

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 429

فایل این مقاله در 8 صفحه با فرمت PDF قابل دریافت می باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

DPFSTS06_280

تاریخ نمایه سازی: 6 شهریور 1398

چکیده مقاله:

Manganese dioxide as an efficient, mild and economical catalyst for one-pot three-component Biginelli synthesis of 3,4-dihydropyrimidin-2-(1H)-one/thione derivatives from reaction between β-keto esters (methyl or ethyl acetoacetate), aromatic aldehyde (benzaldehye derivatives) and urea or thiourea under thermal and solvent-free conditions with good yields and short reaction times is reported. The most benefits of this synthetic method are including efficient, eco-friendly, inexpensive and non-toxic catalyst and solvent-free conditions.

نویسندگان

Farzaneh Mohamadpour

Young Researchers and Elite Club, Shiraz Branch, Islamic Azad University, Shiraz, Iran