Synthesis of Heterocyclic Compounds Bearing Nitrogen and Oxygen Atoms Using Nano-kaoline/BF3/Fe3O4 Based on Green Chemistry in Different Conditions

In recent years, using nano-size solid acids in chemical reactions have been known as aprinciple in development of green chemistry. The efficiency of heterogeneous catalysts can beimproved by employing nanosized catalysts because of their extremely small size and largesurface to volume ratio and act a bridge between homogeneous and heterogeneous catalysts.On the other side, heterocyclic compounds containing nitrogen or oxygen have received muchattention for their biological activities and the wide application in both pharmaceutical andindustrial researches. So, the widespread application of solid acids, structural and practicaldiversity of heterocyclic compounds containing N- or O- have prompted us to employ thenovel and eco-friendly methods for the synthesis of heterocyclic compounds including: 3,4-dihydropyrimidin-2(1H)-ones [1], 1,4-dihydropyridines [2], 2,3-dihydro-1H-perimidines [3],N-arylpyrroles [4], and tetrahydro-4H-chromenes [5,6] using nano-kaoline/BF3/Fe3O4 as agreen catalyst under different conditions. Initially, nano-kaoline/BF3/Fe3O4 were prepared. It̕ sstructure and properties were characterized through the conventional methods of determiningmaterials such as: FESEM, TEM, FT-IR, XRD, EDX, VSM and TGA. Then, this catalyst wasused in the synthesis of some heterocyclic compounds bearing N- and O- atoms. The obtainedproducts have been characterized by FT-IR, 1H NMR and 13C NMR spectroscopy.