A New Strategy for the Synthesis of 2-Mercaptobenzazole Derivatives by Green Chemistry Metrics

A green and efficient method has been developed for the synthesis of 2-mercaptobenzazole derivatives via the reaction of commercially available aniline derivatives with low-cost and non-toxic potassium thiocyanate in water. The reactions proceeded smoothly under catalyst- and ligand-free conditions to give the corresponding products in good to excellent yields. The versatility, low cost, and environmental friendliness, in combination with high yields and easy work-up makes the procedure noteworthy.

کلیدواژه ها:

2-mercaptobenzazoles ، potassium thiocyanate ، aqueous medium ، catalyst-free ، ligand-free.