Marine algae possess therapeutic potential for osteoporosis treatment and bone tissue engineering applications

IntroductionThe marine environment is rich in mineralizing organisms that are used as bone repair and bone graft materials and they are beneficial for treatment of various diseases. Osteoporosis is one of the common bone diseases. In the quest for the appropriate treatment of osteoporosis, researchers are now turning toward nature-based drugs such as marine algae.ObjectivesThe aim of the present review is investigating of functional role of algae on osteoporosis and tissue engineering.MethodsIn this study, articles were examined which indexed in Pubmed, Science Direct and Google Scholar databases.ResultsMarine algae has many health benefits. It has favorable effect on bone metabolism, especially on osteogenesis and was used in bone tissue engineering. Interestingly, a group of red algae deposits calcium carbonate. Research studied introduce a bio ceramic from algae origin, which is suitable for bone tissue application.The positive effect of red algae hydroxyapatite granules have been proven in the manufacturing of three-dimensional cell bone fragments. Calcium carbonate originating from marine algae shows porous characteristic and interconnectivity that makes it similar to human bone. Moreover, several studies have shown that algae improves bone metabolism because it is abundant source of essential minerals.ConclusionThese results provide new insights into the development of new strategies of bone tissue engineering. Additionally, compounds extracted from algae are very biocompatible, and do not have the side effects of synthetic drugs, therefore they have advantageous results for osteoporosis treatment

کلیدواژه ها:

Marine algae ، Osteoporosis ، Bone tissue engineering