Evaluation of the recurrence and 5- year survival in patients with papillary thyroid cancer in Yazd Shahid Sadoughi Hospital from 2008 to 2014

Background & Objectives: Papillary thyroid cancer makes up about 85 percent of the thyroid gland cancer. The tumor is usually in early adulthood and presents itself as a single nodule, Then spreads through the lymphatic vessels into the tumor, through the lymph vessels within the tumor, and then through the surrounding capsule. 80% of children and 20% of adults present with palpable lymph nodes. The tumor metastasize to distant areas such as the lungs and bone. Hence we decided to evaluate the recurrence rate and 5-year survival in patients with papillary cancer.Materials and Methods: This cross-sectional study is that the prevalence of papillary thyroid cancer and survival rates from 2008 to 2014 went with it. The population of 126 patients in this study, were all the cases with papillary thyroid cancer, and the survey was conducted a census. All the patients records including: age, sex, stage of the tumor, lymph node involvement were extracted. The survival rate of the patients was obtained through the hospital records and the phone call. The data were analyzed with SPSS version 21 statistical analysis using descriptive statistics such as mean, median obtained. The log-rank test for survival analysis and Kaplan-Meier curves were used. P-value levels of less than 0.05 was considered statistically as significant.Results: The results show that of the 126 patients, 26 were male and 100 were female. Overall, the mean age of patients was 35 ± 14.25 with a minimum age of 17 and a maximum age of 90 years. 5-year survival rate in patients of this study was 99.2%, and the mean time for recurrence in this survey was 13.3 ± 15 months and the mean tumor size was 2.4 cm. The results also show there is a significant relationship between the survival rate and involved lymph nodes, metastasis and tumor stage. For the relationship between variables and recurrence, our results show that between the recurrence of lymph nodes and metastasis, tumor grade and stage of the tumor, there was statistically significant relationship.Conclusion: In this study, survival rates were similar to other studies and survival rate, significantly, associated with tumor stage. However, the tumor size is not definitive of the survival rate.

کلیدواژه ها:

Thyroid Neoplasms ، Carcinoma ، Papillary ، recurrence ، survival