Maternal vitamin D deficiency can effectively predict increased risk for hyperbilirubinemia in term newborns

Neonatal jaundice is prevalent, and the presence of hyperbilirubinemia frequently requires medical attention and hospital readmission. The aim of the present study was to determine whether serum vitamin D in pregnant women correlates with their newborn jaundice Methods and Material: Serum 25-hydroxyvitamin D was obtained from 300 pregnant women with gestational age of 38-42 weeks who enrolled in this cross-sectional study from March 2018 to August 2018. Bilirubin was measured 3-5 days after birth in their newborns. The obtained data were analyzed using SPSS, version 22.0.Results: The levels of 25-hydroxyvitamin D was low in 277 (92.3%) pregnant women. Hyperbilirubinemia was detected in in 38 (12.6%) newborns at the 3rd-5th days of life. Maternal vitamin D during pregnancy showed a significant correlation with the levels of bilirubin in newborns (r = - 0.458, P<0.001).Conclusion: Vitamin D deficiency is common in pregnant women; this can be associated with neonatal hyperbilirubinemia. It seems that investigators should be encouraged to study new high strength vitamin D supplements for preventing maternal hypovitaminosis D and following neonatal jaundice.

کلیدواژه ها:

hyperbilirubinemia ، jaundice ، mothers ، newborns ، vitamin D