Deuteration of aniline aromatic ring in the presence of Heterogeneous Platinum Catalyst

Deuterated arylamines demonstrate great potential for use in optoelectronic Devices. In this study, a quite simple and post-synthetic method has been reported for D labeling of aniline using a combination of platinum metal on carbon as catalyst and deuterium oxide (D2O) as a D source in the presence of hydrogen gas. Typically, the reactions were carried out in a sealed tube, a mixture of a substrate, heterogeneous Pt/C (20 wt% of the substrate) in D2O was stirred at 80 °C under ordinary hydrogen gas atmosphere for 24h, chemical purity and deuterium isotopic enrichment of the aromatic ring determined by NMR spectroscopy and using internal standard addition method.