Evaluation of general, radiologic and pathologic features of male breast cancer in Shiraz, Iran

Introduction: Male breast cancer (MBC) is an infrequent disease with a limited research. In this study, we aimed to evaluate the general, radiologic and pathologic features of MBC patients to see if there is any specific pattern in this rare disease. Method: We retrospectively review the medical records of MBC patients who had been referred to breast clinic, Shahid Motahari in Shiraz, Iran, between 2000 and 2018. Data regarding demographic information, risk factors, mammogram and ultrasound findings, histopathologic features of primary tumor, lymph node involvement, and metastasis were attained by reviewing medical records. Result: Among 37 MBC patients included in current study. Mean age at time of diagnosis was 57.4 years (ranging from 37–83 years). Infiltrative ductal carcinoma was found in 78.3% of patients and 8% with papillary cell carcinoma. The histopathological diagnosis of 5 breast tumors was missed. Most of the tumors were diagnosed in stage 2 (43 %).Regional lymph node involvement were diagnosed in 44% of patients, and 19 % patients had distant metastasis at the time of diagnosis. Mammography was performed on 24 % of patient with 100 % accuracy. 40% of patient also had diagnostic ultrasound which 80 % showed mass lesion, 13 % non-mass lesion and one of the patients was misdiagnosed with gynecomastia. Conclusion: This study showed that despite increasing incidence of MBC, diagnostic modalities are postponed and neglected up to later stages. Therefore, MBC screening by imaging modalities in high risk people should be considered.

کلیدواژه ها:

male ، breast ، cancer ، radiology ، pathology