Probability of ACL tear in the contralateral knee and sibling

Backhrounds Recent studies have shown that several genetic factors can cause an individual›s susceptibility to anterior cruciate ligament (ACL) rupture. The aim of thepresent study was to evaluate certain underlying factors in increasing the risk of ACLrupture.Methods Eight hundred thirty-six patients with ACL rupture, who had undergone ACLreconstructive surgery from 2010 to 2013 in an academic center and at least 5 yearshave passed since their surgery, were enrolled. Our variables included gender, age,height, weight, exercise level, time interval between ACL rupture in the first knee andcontralateral ACL rupture, the dominant leg, the side of involved knee and the historyof ACL rupture in the patient›s sibling. Data were analyzed using SPSS version 21.Results Mean follow-up of patients was 6.9 years. Eighty-three patients (%9.9) hadcontralateral ACL rupture and 155 patients (%18.54) had history of ACL rupture intheir siblings. Based on our results, contralateral ACL rupture was three times higher inwomen compared to men and in patients with history of ACL rupture in sibling comparedto who without this history. In addition, the risk of contralateral ACL rupture was higherin age lower than 30 years, BMI 25-20 kg/m2 and who with regular sport activity.However, the dominant or defeated damaged knee had no effect on the incidenceof contralateral ACL rupture. Our results indicated that %83.13 of contralateral ACLrupture occurred during the first two years after the primary operation.Conclusions The risk of contralateral ACL rupture and ACL rupture in sibling in the 6.9years› follow-up is %9.9 and %18.54, respectively. Also, the risk of contralateral ACLrupture is 3 times higher in women than in men.