Study of trends in antibiotic resistant Acintobacter infections and effective factors due to decreasing resistant Acintobacter in General ICU, Shafa hospital, Kerman, 2013-2018

Introduction: Antibiotic resistant bacteria‟s are challenges to the words health systems. They lead to increase morbidity, mortality and costs. These bacteria‟s are able to spread quickly. This study aimed to determine trends in antibiotic resistant Acintobacter infections and effective factors due to decreasing resistant Acintobacter in General ICU, Shafa hospital, Kerman.Materials and methods: This cross sectional study was conducted in ICU for 4.5 years and 3 periods included: 6 month (2013-2014) for before intervention (period 1), 1 year (2014-2015) for intervention (period 2) and 3 years (2015 -2018) for after intervention (period 3).Passive surveillance in patients with positive culture was used. Resistance to antibiotics was performed by disk diffusion method. Control of drug resistance program included: Appropriate hand hygiene, contact precautions, training, isolation and environmental hygiene practices. Data were collected using HIS system & laboratory.Results: Before the intervention (period 1), the rate of pan drug-resistant Acinetobacter baumannii colonization and/or infection was 33.9 cases per 1000 patient-days. In intervention period, this rate decreased to 15.8 cases per 1000 patient-days (P<0.1). In the period 3 this rate decreased to 11.2 in 2015-2016, 5.5 in 2016-2017 and 0.33 in 2017-2018.Contact precautions in period 2 increased to 90% (from 30% in period1) and hand hygiene compliance increased to 50% (from30% in period1). In the 3 years of period 3 hand hygiene140increased to 60% and Contact precautions stayed 90% and proper management of prescription of antibiotics .Conclusion: The results of this study demonstrate the effectiveness of prevention programs to reduce and prevent of resistant strains spreads. According to devastating effects of these strains presence on the health system, existence of a national/regional prevention program with highsupervision is needed.

کلیدواژه ها:

antibiotic resistance Acintobacter ، monitoring program ، ICU