Prevalence and antibiotic resistant patterns on isolated Escherichia coli from different words Bouali Sina Hospital Sari(2018)

Introduction and Objectives: Escherichia coli (E.coli) is an opportunistic Gram-negative bacterium, which causes common nosocomial infections, including pneumonia, septicemia, meningitis, diarrhea, bacteremia, etc. Urinary tract infection (UTI) is one of the most common nosocomial infections. Antibiotic resistance patterns vary in different regions. The aim of this study was to determine the antibiotic resistance patterns and to detect Escherichia coli in clinical isolates. Materials and Methods: The clinical specimens were collected from patients during 9 months. Using routine microbiological methods, we identified the bacteria. The antibiotic resistance pattern of the isolates was detected by the disk agar diffraction method.Result: Out of 13322 Clinical samples 870 (6.53%) Escherichia coli isolates were identified Based on the results of antimicrobial resistance test, the highest resistance was with ampicillin (62.5%), cephalexin (39.31%) and nalidixic acid (26.66%). Furthermore, the highest sensitivities belonged to amikacin (97.81%), Imipenem and tobramycin ,(94.59%), and meropenem (62.50%), respectively.Conclusion :The results showed an increase in strains of Escherichia coli to antibiotics Ampicillin,cephalexin and nalidixic acid, which may cause irregular use of this antibiotics. It is recommended that the unnecessary use of antibiotics must be avoided.

کلیدواژه ها:

Antibiotic resistance ، Escherichia coli ، bacterias