Antibacterial properties of microalgae Spirulina platensis, Haematococcus pluvialis, and Chlorella vulgaris extracts

Introduction: Microalgae are cultured commercially and their products are used in various clinical treatmets.116Methods: In the present investigation the antibacterial properties of different solvent extracts of these three commercial microalgae Spirulina platensis, Haematococcus pluvialis and Chlorella vulgaris were evaluated. Results: The maximum phenolic contents (128, 131, 110 μg/mg) was recorded in chloroform extracts of S. platensis, H. pluvialis and ethyl acetate extract of C. vulgaris. Hexane, chloroform, ethylacetate, acetone and methanol extracts of S. platensis, C. vulgaris and H. pluvialis were tested against important clinical bacterial isolates such as Bacillus subtilus, Bacillus cereus, Enterobacter aerogenes, Escherichia coli, Klebsiella pneumoniae, Listeria monocytogenes, Micrococcus luteus, Proteus mirabilis, Pseudomonas aeruginosa, Salmonella typhi, Staphylococcus aureus, Streptococcus fecalis and Yersinia enterocolitica. The antibacterial activity was determined by agar-well diffusion assay and minimum inhibitory concentration (MIC). Chloroform and ethyl acetate extracts of S. platensis showed highest inhibition against B. subtilus (18.12 mm and MIC at 200 ppm), while chloroform extract of H. pluvialis recorded highest inhibition against B. subtilus (17.32 mm and MIC at 150 ppm). In C. vulgaris, ethlyacetate extract exhibited maximum inhibition against E. aerogenes (15.11 mm and MIC at 300 ppm). Conclusion: The results of this research demonstrated that extracts of microalgae have useful antibacterial activity and can be used as bacteriostatic agents in clinical applications.

کلیدواژه ها:

Microalgae extract ، Antibacterial properties ، Bacteriostatic agent ، Microalgal treatment