applications of nanotechnology to solve challenges of neural tissue engineering

According to the anatomical and physiological structure of the nervous system, regeneration and repair of the nervous system is complex. Extensive studies in this field such as stem cell therapies and tissue engineering, nerve regeneration has provided new methods. Recent advancements in nerve regeneration have involved the application of tissue engineering principles and this has evolved a new perspective to neural therapy. Tissue engineering involves seeding of cells on bio-mimicked scaffolds providing adhesive surfaces. However researchers though face a range of problems in generating tissue which can be circumvented by employing nanotechnology. Nanotechnology provides substrates for cell adhesion and proliferation and agents for cell growth and can be used to create nanostructures and nanoparticles to aid the engineering of different types of tissue. Gold NPs (AuNPs) are of particular interest due to their excellent stability and various biocompatibility properties, including nontoxicity, non-immunogenicity, and high tissue permeability without hampering cell functionality. (AuNPs) can be incorporated into macro porous scaffolds or other bioengineering materials to increase the conductivity and enhance the electrical signal transfer between neural cell.