The clinical, Ultra-sonographic and histopathological profiles in gestational trophoblastic diseases, Kosar Hospital
محل انتشار: هفدهمین همایش سالانه آسیب شناسی و طب آزمایشگاه
سال انتشار: 1394
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 383
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شناسه ملی سند علمی:
ACPLMED17_111
تاریخ نمایه سازی: 20 آبان 1397
چکیده مقاله:
Background: Hydatidiform mole is a kind of gestational trophoblastic disease (GTD) and is the most common form.About 80% of hydatidiform mole are not cancerous and regress, impromptu. Regarding 15-20% invade encompass tissue and tend to persist. Of these invasive moles, 2-3% become cancerous and extends throughout the body through the lymphatic vessels or bloodstream. Hydatidiform mole diagnosis is performed by pre-evacuation ultra-sonographic study, lab tests and ultimately histopathological examination as gold standard. The present study was undertaken to evaluate the clinical, Ultra-sonographic and histopathological profiles in gestational trophoblastic diseases, Kosar Hospital.Materials and methods: This was a cross-sectional study conducted among the 120 patient with clinical impression of molar pregnancy that undergone suction and sharp curettage who referred to Kosar Hospital from April 2012 to April 2014. The data from these participants were obtained by a check list (demographic data and clinical presentations) and histopathology report. Both descriptive and statistical analysis methods were applied value < 0.05 was significant.Result: Out of 120 cases with clinical impression of molar pregnancy, 105 cases were confirmed by histopathological diagnosis. Age range of subjects in this study was 17-38 years. The most frequent presentation was vaginal bleeding in the first trimester. The summarizing histopathological diagnosis comprises: 21 cases of complete mole, 80 partial moles and 4 invasive moles. Aside from 105 cases with histopathological diagnosis mole only in 6 cases misdiagnosed by ultrasonoghraphy (4.1%) therefore high degree of agreement between ultrasonography and histopathological diagnosis is seen.Conclusion: Routine sonography in first trimester is advised for early. Ultrasonographic study joined with clinical presentations, and histopathological evaluation as gold standard have high efficacy in diagnosing mole.
کلیدواژه ها:
نویسندگان
Talat Dabbag
Associated professor of Gynecology and Obstetric, Qazvin University of Medical Scienes.Qazvin , Iran
Fatemeh Samiee Rad
Associated professor of Pathology. Qazvin University of Medical Scienes.Qazvin , Iran
Fatemeh Mohammadi
PhD, Assistant Professor. Nursing and Midwifery Qazvin University of Medical Sciences
Mahsa Ziaee-Ardestani
Resident of Pathology. Tehran University of Medical Scienes.Tehran , Iran