A SEROLOGICAL SURVEY ON COXIELLA BURNETII IN PREGNANT WOMEN WHO WERE HISTORICAL ABORTION IN KHORRAMABAD, WESTERN IRAN

Background and Aim:Q fever is zoonotic disease caused by Coxiella burnetii , this bacteria is gram negative obligate intracellular. This disease have different clinical symptoms such as spontaneous abortion, premature birth, intrauterine growth retardation, oligoamonios and abnormal pregnancy in pregnant women. The aim of this study was to investigate the seroprevalence infection of C.burnetii in pregnant women who were historical abortion in Khorramabad (western Iran).Methods:A total of 184 samples were collected randomly from pregnant women who reffered to clinical laboratory and center health in Khorramabad in 2017. Were exmined using indirect ELISA assay kit for the detection of C.burnetii phase II human antibodies in their serum sample.Results:The total 184 serum samples from pregnant women, 39 sample was historical abortion that 19 sample(48/7%) was positive and 15 sample(38/5%) was negative and 5 sample(12/8%) was suspected.there is not statistically significant(pv=0/820).Conclusion:According to result of this study, high prevalence of Q fever in pregnant woman who had historical abortion is necessary in due to the complexity of symptoms this disease in pregnant women,.For preventation and cure of unwanted side effects of this disease, pregnant women should pay more attention to this disease.

کلیدواژه ها:

Serological ، Coxiella burnetii ، Women Pregnant ، Abortion