STUDY THE PREVALENCE OF RESISTANCE GENE, QACE TO QUATERNARY AMMONIUM COMPOUNDS IN THE ISOLATED ACINETOBACTER BAUMANNII OF HOSPITAL OF QAZVIN (2015-2016)

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 390

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شناسه ملی سند علمی:

MEDISM19_229

تاریخ نمایه سازی: 13 مهر 1397

چکیده مقاله:

Background and Aim:Acinetobacter baumannii is one of the important agent of hospital infections. In recent years, there are several report about frequency of resistant acinetobacter against quaternary ammonium compounds (QACs) in the clinical unit of hospitals in the world. It has used different antiseptics and disinfectants for preventing hospital infections in clinical centers and hospitals. QACs like benzalkonium has widely used as wound and skin antiseptic and hospital disinfectant. The mechanism of resistance to disinfectants was happened by resistance genes type qacE that was isolated from gram negative bacteria. As the importance of preventing hospital infection due to acinetobacter, the aim of this study, was to determine prevalence of resistance gene, qacE to disinfectant in the clinical isolated acinetobacter baumanniiMethods: Totally, 141 isolated acinetobacter baumannii were studied from specimens of hospital of Qazvin Province from Sep 2015 for year. The isolated were characterized as acinetobacter baumannii via standard methods. Then, all isolated were studied using polymerase chain reaction (PCR) and sequencing for qacE resistance geneResults:Isolated acinetobacter of trachea, urine, and blood were 82(58%), 23(16%), 14(9%) respectively from all specimens. Also, 24 (17%) isolated have qacE gene and the most frequency of isolated acinetobacter baumannii that contain qacE gene were in ICU 14(58%). The result of this study showed the significant resistance to disinfectants in the evaluated hospitalsConclusion:Thus, more attention to acinetobacter baumannii as an important agent in the hospital infection and applying disinfectant is necessary

نویسندگان

Samaneh Keshavarz Hedayati

Department of Microbiology, Zanjan Branch, Isiamic azad university, Zanjan, Iran

Amir Peymani

Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran

Narges Habibollah Pourzereshki

Medical Microbiology Research Center, Qazvin University of Medical Sciences, Qazvin, Iran