Socio-economic Factors Related to Estimated Risk of Affecting to Breast Cancer by Gail Model in Women Older than 35 Years Referring to Health Centers of Zahedan City in 2016

Introduction and Aim: Breast cancer (BC) is the most common cancer among Iranian women and around the world that has increasing trend in Iran in recent decades. This study was aimed to assess socio-economic and menstrual-reproductive factors related to estimated risk of BC in southeast of Iran.Methods: This cross sectional study was conducted on 260 women more than 35 years old referring to health centers in Zahedan. The data was collected by interview using a structured questionnaire. Breast Cancer Risk Assessment Tool calculated the Gail risk for each subject. In addition to bivariate analyses, multiple linear regression was used to predict the effect of each variable on the risk controlling for confounders.Results: The mean age of the participants was 48.5 ± 7.6 years old. The 5 years and lifetime risk was 0.36 ± 0.21 and 5.3 ± 0.82 percent, respectively. Positive family history of BC, higher age of first live birth and age were related to higher 5 years risk (P<0.05). A significant direct correlation observed between lifetime risk with positive family history of BC, higher body mass index (BMI), higher age of first live birth,Fars ethniety and history of divorce (P<0.05). Conclusion: The risk of BC based on Gail model is not higher than expected level. Regarding to approving the known risk factors of BC in previous studies, the modified Gail model for women in southeast of Iran could be offered including the effect of known risk factors such as ethnicity, BMI, during of breastfeeding and history of divorce.

کلیدواژه ها:

Breast cancer ، Gail model ، Iran ، risk factors