The importance of diffusion weighted imaging in breast MRI
- سال انتشار: 1394
- محل انتشار: دوازدهمین کنگره بین المللی سرطان پستان
- کد COI اختصاصی: ICBCMED12_140
- زبان مقاله: انگلیسی
- تعداد مشاهده: 410
نویسندگان
Department of Biomedical Engineering ,Islamic Azad University ,Science and Research Branch Tehran, Iran
Department of Biomedical Engineering and Medical Physics ,Tehran University of Medical Sciences ,Tehran ,Iran
Department of Biomedical Engineering and Medical Physics ,Tehran University of Medical Sciences ,Tehran ,Iran
Quantitative MR imaging and Spectroscopy Group Research Center for Molecular and Cellular Imaging ,Tehran, Iran
چکیده
Aim: the aim of this study was to evaluate the value of diffusion weighted imaging in Diffusion weighted imaging in distinguishing between in benign and malignant breast lesion Materials and methods: There were 37 female patients with 47lesions. Sixty seven female subjects (40mean age ) ,age ranges 17-69 , with histopathologically proven breast lesions underwent DWI of breasts with a single shot echo planar imaging (EPI )sequence .the computed mean apparent diffusion coefficients (ADCs) of the breasts lesion and cell density were then correlated . Results: The ADC varied substantially between benign breast lesions ((1.52±0.26) ×10 -3 mm2/second). And malignant breast lesions ((0.94±0.21)× 10 -3 mm2/second) .The AUC with ROC analysis was 0.896 and the threshold for ADC was 1.17 ×10-3 mm2/s with a sensitivity and specificity of 90% and 85%, respectively. The mean ADC of malignant breast lesions was statistically lower for benign lesions (p< 0.01) Conclusion: The ADC would be a effective parameter in distinguishing between malignant and benign breast lesionsکلیدواژه ها
Apparent diffusion coefficient, breast cancer, breast imaging, diffusion-weighted imagingمقالات مرتبط جدید
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