Time-to-Ejaculation and the quality of semen in fertile and infertile men

Background: The average time it takes for ejaculation to occur upon stimulation varies between individuals, with no strict figure given for what is normal. In the present study, we have investigated the association between the length of time-to-ejaculation and semen parameters which was produced by masturbation. Ejaculated semen of fertile and infertile men submitted for ICSI program at Avicenna Infertility Clinic (AIC) were included in this study.Methods: Three groups in each category (fertile and infertile) were defined according to time to ejaculation: G115 min. Each specimen was produced after 3-4 days of ejaculatory abstinence. Two different experiments were conducted: In 55 fertile men (group 1) attending for family balancing through ICSI/Sex selection program and in group 2, 49 infertile men submitted for ICSI/ET program. Measures included the time taken to produce ejaculate, sperm count, morphology and motility, SDF (sperm DNA fragmentation) and SCI (sperm chromatin immaturity). Additionally, the fertilization rate and embryo quality were analyzed within three different times in each group.Result: No significant correlations existed among the time-to-ejaculation, men age and sexual abstinence. The present study demonstrated that increased time-to-ejaculation during masturbation at IVF clinic was not associated with remarkably poorer semen parameters in terms of sperm count, progressive motility and morphology between samples in group 1 and 2 in three defined time to ejaculation. Also functional parameter of semen including SDF and SCI showed no significant difference in two groups.Conclusion: Moreover, there was not any major difference in the fertilization rate and embryo quality in two groups regarding three different time to ejaculation.

کلیدواژه ها:

Fertilization rate ، Sperm chromatin maturity ، Sperm DNA fragmentation ، Time-to-ejaculation