Epidemiology Of Childhood Cancer In Northeast Iran Between 2006-2014

Malignant neoplasms remain the second leading cause of death in children after accidents andLeukemia is the most common malignancies in t. The aim of this study was to assess epidemiology ofchildhood cancer in Northeast Iran. This descriptive cross- sectional study has been done in DrSheikh Hospital in Mashhad University of medical science in Iran on 1764 children younger than 14years old during 2006-2014 with cancer that has been pathologically confirmed. All informationabout the age, sex, type of cancers and residence of patients were collected from their medicalrecords.For classification of the lesions the tenth edition of International Classification ofChildhood Cancer (ICCC‐10) coding system was used. 1764 forms were completed and the data wereanalyzed by SPSS-21. Required data such as sex, age, pathology of cancer, place of residence werecollected and included in a checklist form. Frequency distribution of childhood cancers in less than14 year old was evaluated and incidence rates were calculated per 1000,000 people a year. 1047(59.4%) of cases were male and rest of them were female by sex ratio 1.5 to 1. The mean age ofpatients was 5.8± 4.2 and 30% were in age group 3-6 years. 1186(67%) of cases were from Razavikhorasan province. Results showed that leukemia (56.4%), Lymphomas (10.4%), renal tumor (9%),malignant bone tumor (4.4%) and CNS tumor (4.1%) were the most prevalent malignancies inNortheast Iran. Form leukemia cases (86.9%) were acute lymphatic leukemia (ALL). Over in nineyears period, lowest and highest age standardized incidence rate was 114 (year 2006) and 142 (year2014) cases per every 1000,000 person, respectively. The frequency of malignant diseases is morecommon in males than in females which are the same as other studies. The frequency anddistribution of malignant diseases is the most in children aged 3-6 years that is different from somestudies. Leukemia is the most prevalent malignant disease in the pediatrics which followed bylymphoma and renal tumor, that is different from some studies. In most study CNS tumor was thesecond malignancy, but as the majority of children with CNS tumor admitted in another hospital, itwas reported lower the another study.