Exceedingly Expedient Route Toward Ambient Preparation of Novel[1,3]Dioxolo[g]chromene Derivatives Catalyzed by Ag/CdS Nanocomposite

Chromene derivatives are a privileged of heterocyclic system, which exhibit a variety of biological properties such as antioxidant, anticancer, antimicrobial, and etc. [1, 2]. Nowadays, nanostructured metal sulfides are used as catalysts in organic synthesis because of their special features such as high surface area with low coordination sites [3-5]. In the present work a novel and efficient synthesis of new 8-aryl-8H-[1,3]dioxolo[4,5- g]chromene-6-carboxylic acids 5 was reported from the cyclocondensation reaction of arylmethylidenepyruvic acids 3 with 3,4-methylenedioxyphenol 4, in the presence of a catalytic amount of Ag/CdS nanocomposite (15 mol%) at room temperature in aqueousmedia (Scheme 1). The arylmethylidenepyruvic acids 3 were prepared by method reported [6].

کلیدواژه ها:

Ag/CdS nanocomposite ، Aqueous media ، [1 ، 3]Dioxolo[g]chromenes ، Eco-friendlyprocedure