CuI NPs Catalyzed Efficient and Eco-Friendly Synthesis of 3-Amino-1Hchromenesin Aqueous Media

Chromenes show considerable interest in the medical and pharmaceutical industries, since they exhibit a broad range of biological activities such as antioxidant, anticancer, antimicrobial, and etc. [1, 2]. CuI NPs is attractive metal salt nanoparticles catalyst because of its unique properties such as being non-toxic, inexpensive, moisture stable and reusable catalyst [3-5]. Herein a very simple and environmentally benignapproach for the synthesis of some of 3-amino-1aryl-1H-benzo[f]chromene-2-carbonitriles 4 is described via a three-component condensation of β-naphthol 1, aromatic aldehydes 2, and malononitrile 3, using CuI NPs as an efficient heterogeneous catalyst in green media, namely water

کلیدواژه ها:

Aqueous media ، 3-Amino-1H-chromenes ، CuI NPs ، Environment-friendly procedure