Evaluation of Aspirin Structure in the Solvent Phase

Many chemical reactions take place as a result of entering the reactant in the solvent phase.The interaction between the solvent and solute can have various effects on its energy state,structure as well as its molecular properties. Usually, such effects can be calculated usingsolvation models. In this study, we aimed to evaluate the effect of different solvation models,the type of the solvent and the temperature on the stability of the aspirin crystal.