Theoretical study on conformers of tyrosine and tyrosine complexes with ozone molecule by DFT method

Tyrosine is one of the 22 amino acids that are used by cells to synthesize proteins. It is a nonessentialamino acid with a polar side group. Its codons are UAC and UAU. Aside from beinga proteinogenic amino acid, tyrosine has a special role by virtue of the phenol functionality. Itoccurs in proteins that are part of signal transduction processes. It functions as a receiver ofphosphate groups that are transferred by way of protein kinases (so-called receptor tyrosinekinases). Phosphorylation of the hydroxyl group changes the activity of the target protein [1].In this work, we determine the most stability of geometric structure of the tyrosine moleculein the gas, aqueous and ethanol phases and tyrosine molecule interaction with ozonemolecule.