Formation of flake-like hydroxyapatite on synthesized β-TCP/ bioactive glass nanocomposite

In the present research, nano-bioactive glass in the ternary system 58SiO2-33CaO-9P2O5 (N-58BG) was synthesized by a quick alkali-mediated sol–gel method. The morphology was analyzed by transmission electron microscope (TEM). A certain amount (3wt%) of N-58BG was then added to beta-tricalcium phosphate (β-TCP). The nanocomposite sintered at 1200°C and changes in physical and mechanical properties were investigated and compared with the pure β-TCP. The X-ray results showed that N-58BG additive did not change the phase composition of β-TCP. The maximum compressive strength (~63 MPa) was achieved for 58BG/β-TCP nanocomposite. The morphological observations (evaluated by scanning electron microscopy (SEM)) indicated that the micropores of pure β-TCP were decreased by adding N-58BG. Based on acellular in vitro studies, apatite crystals with the flake-like nanostructure were formed on the surface of BG/β-TCP nanocomposite after 7 days of soaking in simulated body fluid (SBF). As a consequence, BG/β-TCP nanocomposites with improved mechanical and bioactive properties can be obtained using certain quantities of bioactive glass nanoparticles.

کلیدواژه ها:

Sol-gel derived nano-bioactive glass ، Beta-tricalcium phosphate ، Compressive strength ، Flake-like hydroxyapatite