Microscopic Transsphenoidal Surgery for Pituitary Adenomas in Children and Adolescents

Background & Aim: We described the presentation, management and subsequent treatment outcomes of children andadolescents diagnosed with a pituitary adenoma in a joint neuroendocrine setting followed up by a single service aswell as assessing long-term outcomes in terms of endocrine status and neurology symptoms.Methods & Materials/Patients: A total of 21 participants with histologically verified pituitary adenoma betweenJanuary 2011 and June 2014 were studied. Patients' data from clinical, radiological and pathological records wereanalyzed using SPSS (Version 16).Results: All these children and adolescents with pituitary adenomas were managed with microscopic transsphenoidalsurgery. The most common symptom was Cushing (47.6%, n=10). The functional type (76.2%, n=16) was more thanthe non-functional. The post-operative control MRI of most of them was clear (90.5%, n=19). The lab control of mostof them was normal (76.2%, n=16). Apoplexy was seen in 5 patients (33.8%). Gross-total resection (GTR; 100% tumorremoval as judged by early post-operative imaging) was achieved in 19 cases. Only one of these patients showedevidence of radiologic recurrence.Conclusion: In our study, all patients underwent microscopic transsphenoidal surgery due to limitation of endoscopicapproach in pediatric and avoided wide anatomical deficit. Doing a comparative study between these two approacheswill bring about promising results.

کلیدواژه ها:

Pediatric Pituitary Adenoma ، Apoplexy ، Transsphenoidal Approach ، Functional Pituitary Adenomas ، NonfunctionalPituitary Adenomas