Synthesis of 2,4-diamino pyrimidine-5-carbonitrile derivatives using sulfonic acid-functionalized mesoporous LUS-1

Propyl sulfonic acid functionalized LUS-1 was used as a recyclable heterogeneous catalyst in the synthesis of 2,4-diamino pyrimidine-5-carbonitriles via condensation reaction of aromatic aldehydes, malononitrile and guanidine carbonate in solvent-free conditionThis green method offers a number of advantages such as short reaction time, good yields, simple work-up procedure, recyclable catalyst and environmentally friendly conditions.

کلیدواژه ها:

sulfonic acid functionalized LUS-1 ، 2 ، 4-diamino pyrimidine-5-carbonitrile ، guanidine carbonate ، solvent-free condition