CHOLESTEROL REMOVAL EFFECT AND BILE SALT HYDROLASE BY PROBIOTIC LACTIC ACID BACTERIA

Dietary habit change toward lipid-rich foods in recent years has resulted in risks for cardiovascular diseases. Serum cholesterol level is commonly recognized as an important factor in disease development. In this case, one of the most significant groups of probiotic organisms are the lactic acid bacteria, probiotics are live microorganisms that promote health benefits upon consumption, they could be used as alternative supplements to exert health benefits, including cholesterol-lowering effects on humans. However, little information is available on the effective dosage of probiotics needed to exert hypocholesterolemic effects. Both probiotics and prebiotics have been suggested to reduce cholesterol via various mechanisms. Though, more clinical evidence is needed to strengthen these proposals. The objective of this article was to review existing literature concerning the effects and mechanisms of action of probiotics on serum cholesterol concentrations.

کلیدواژه ها:

probiotic ، cholesterol-lowering ، bile ، bile salt hydrolase