Background and Objective: Assessing women’s literacy about breast cancer is essential to identify existing knowledge gaps and design effective interventions. To translate, culturally adapt, and psychometrically evaluate the
Breast Cancer Literacy Assessment Tool (B-CLAT) for use among Iranian women.Materials and Methods: This methodological study was conducted in ۲۰۲۴–۲۰۲۵ among ۴۰۰ women attending comprehensive health service centers in Tehran, Iran, selected through multistage sampling, to translate and validate the B-CLAT, originally developed in the U.S. The translation process followed the standard forward–backward method by two independent translators in each phase. Face validity was assessed by ۱۰ women, and content validity by ۱۰ experts, according to standard methodological practice. content validity ratio and content validity index were calculated. Construct validity was examined using confirmatory factor analysis and the known-groups method, comparing literacy scores by age and education. Reliability was determined through internal consistency (Cronbach’s alpha) and stability (Intra-class Correlation Coefficient) in a sample of ۳۰ participants. Data were analyzed using SPSS ۱۶ and EQS ۶.۴ software.Results: Most participants were aged ۳۰–۳۹ years (۴۶%), married (۸۲.۵%), and had a university degree (۶۹.۳%). The cultural adaptation of the Persian version showed satisfactory equivalence. The overall CVI was ۰.۹۴۲, indicating strong content validity. CFA confirmed acceptable model fit indices (RMSEA=۰.۰۶۳, IFI=۰.۹۱۳, CFI=۰.۹۰۳, GFI=۰.۹۱۹, CMIN/DF=۲.۹۵۶, MFI=۰.۹۳۳, AGFI=۰.۹۰۰). Known-groups comparison showed no significant relationship between literacy scores and age (P>۰.۰۵), but a significant association with education level (P<۰.۰۵), confirming construct validity. Reliability analysis indicated acceptable stability (ICC=۰.۸۶۸) and internal consistency (α=۰.۷۲۲).Conclusion: The Persian version of the
Breast Cancer Literacy Assessment Tool (IB-CLAT) demonstrated good validity and reliability. It can effectively assess breast cancer literacy among Iranian women, guide educational interventions, and promote screening and prevention behaviors.