Medication Error in Eastern Mediterranean Region Hospitals: A Meta-analysis

Background: Medication errors (MEs) are a major worldwide concern associated with significant clinical consequences for patients.Aim: The purpose of this research was to determine the prevalence of MEs in hospitals in the Eastern Mediterranean Region (EMR) through a meta-analysis.Method: We conducted a systematic literature search up to January ۲, ۲۰۲۴, using PubMed, Web of Science, Scopus, and Google Scholar to identify all observational studies conducted in EMR hospitals that reported the prevalence of medication errors. The total ME rate was calculated using a random-effects model, and heterogeneity was assessed using the I² statistic. The Comprehensive Meta-Analysis software (Version ۲.۲.۰۶۴) was used for data analysis.Results: A total of ۲۲ studies were included in this meta-analysis. The overall ME rate in EMR hospitals was estimated at ۰.۱%. The highest rate was observed in Iran in ۲۰۱۵ at ۵.۱% (۹۵% CI: ۴.۰%–۶.۲%). Moreover, sample size and publication year were significantly correlated with ME rate (p<۰.۰۵).Implications for Practice: Based on the synthesis of the research findings, the prevalence of MEs in EMR hospitals is low. However, preventive and corrective actions remain necessary, given that MEs are not only costly but also harmful to patients.

کلیدواژه ها:

Eastern Mediterranean Region ، Hospital ، Medication error ، Meta-analysis