Ruptured Pyometra Associated with Septic Splenomegaly and Ischemic Necrosis in a ۱۲-Year-Old Shih Tzu Dog

Background: Pyometra is a common, life-threatening uterine infection of intact female dogs that typically develops during the luteal phase due to prolonged progesterone influence. In advanced stages, bacterial endotoxemia and sepsis may lead to systemic inflammation and multi-organ compromise. Although splenic changes are occasionally observed in septic conditions, splenic congestion and ischemic necrosis secondary to septic shock are extremely rare and clinically significant complications. Methods: A ۱۲-year-old intact female Shih Tzu presented with anorexia, vomiting, lethargy, and purulent vaginal discharge. Hematologic analysis revealed severe leukocytosis, while ultrasonography suggested pyometra with systemic infection. The dog underwent exploratory laparotomy under inhalational anesthesia, revealing a ruptured pyometra and splenic abnormalities. Results:The uterus was ruptured with purulent peritoneal contamination. The spleen was markedly enlarged, congested, and mottled with yellow necrotic foci. No vascular torsion was detected. Ovariohysterectomy and splenectomy were successfully performed, and histopathology confirmed ischemic necrosis consistent with septic splenomegaly. Conclusion:This report documents a rare coexistence of ruptured pyometra and septic splenomegaly with ischemic necrosis. It highlights the importance of recognizing sepsis-induced vascular compromise in splenic pathology and demonstrates that prompt surgical intervention and intensive postoperative management can result in a favorable outcome.

کلیدواژه ها:

Dog ، Pyometra ، Splenomegaly ، Sepsis ، Ischemic necrosis