Background: Salmonella enterica is a major foodborne pathogen and a prominent cause of infectious gastroenteritis worldwide, primarily linked to contaminated poultry products. It is responsible for an estimated ۹۳ million annual cases of gastroenteritis worldwide, imposing economic burdens estimated in the billions of dollars in the USA and the EU. Poultry is a major reservoir, accounting for approximately ۴۰% of human salmonellosis cases. The emergence of antimicrobial resistance (AMR) presents a critical global health threat. The misuse of antibiotics in poultry farming has fueled this problem, which could lead to millions of deaths by ۲۰۵۰ and prompted the WHO to classify Salmonella as a "priority pathogen". This study aimed to analyze antibiotic resistance in Salmonella isolates from fresh & portioned chicken. Specifically, it aimed to determine the prevalence, dominant serotypes, and antibiotic resistance patterns, focusing on the genetic basis and mechanisms of resistance to key antibiotics, including β-lactams and macrolides. Methods: Samples collected from ۱۵ fresh cut-up chickens were cultured on blood and MacConkey agars. Antibiotic susceptibility was tested by disk diffusion method using streptomycin, penicillin, gentamicin, ceftriaxone, tetracycline, azithromycin, erythromycin, lincomycin, and vancomycin. For Salmonella isolation, ۱g samples were pre-enriched in peptone water, then transferred to Rappaport-Vassiliadis broth, and finally streaked on MacConkey, Salmonella-Shigella, Triple Sugar Iron, and Xylose Lysine Deoxycholate agars. Salmonella-positive isolates were evaluated using antisera for the enteritidis serotype. Results: Out of the ۱۵ samples taken from cut-up chickens, Salmonella was isolated from ۱۰ cases(۶۶.۶%). Among these ۱۰ positive samples, ۴ (۴۰%) were identified as belonging to the serotype enteritidis. In the antibiogram test, resistance to the antibiotics vancomycin and penicillin was observed.