The Relationship between the Type of Respiratory Support and Its Outcomes in Patients with COVID-۱۹ Hospitalized in the Intensive Care Units

Given the unknown nature of the COVID-۱۹  and the ambiguity surrounding the efficacy of various methods of treatment, the present study aimed to elucidate the correlation between the type of respiratory support administered and the resultant outcomes for patients with COVID-۱۹ who were admitted to the intensive care units. In this retrospective cohort patients’ records were categorized into two groups based on the type of respiratory support method employed: those who were solely intubated and those who received a combined mechanical ventilation approach utilizing an oxygen mask and intubation non-invasive ventilation plus intubation. The instrument used for collecting data comprised a form that encompassed demographic details alongside a history of pre-existing conditions and parameters pertinent to the patient's health status. A comprehensive examination of ۲۶۰ files was conducted. Approximately ۴۶% of the patients were categorized within the intubated group. The findings indicated that, the mean arterial oxygen levels were recorded at four distinct time points-upon hospital admission, upon ICU admission, prior to ventilator support, and following ventilator support- were statistically significant difference (P<۰.۰۰۱). The mean duration of hospitalization for the intubated group was markedly less than that of the group receiving NIV plus intubation (P < ۰.۰۰۱). The mean duration of being connected to a ventilator among the groups under investigation did not yield a statistically significant result. The analysis demonstrated no statistically significant difference in mortality rates between the two groups. Furthermore, examining survival curves revealed a statistically significant distinction between the two groups (P < ۰.۰۰۱). The results partially depend upon potential disparities in the effectiveness of invasive versus non-invasive methods. Consequently, further research in this domain appears imperative to corroborate a more robust endorsement for non-invasive techniques—attributable to their reduced side effects, user-friendliness, minimal training requirements, and broader clinical applicability.

کلیدواژه ها:

COVID-۱۹ ، Non-Invasive Ventilation ، Oxygen therapy ، Intubation ، Respiratory Support