Comparison of the Effects of Ketamine and Dexmedetomidine on the Incidence of Adverse Events (Nausea and Vomiting, Shivering, Hypotension, and Bradycardia) Following Traumatic Nasal Surgeries

Introduction: Evaluating the comparative effects of ketamine and dexmedetomidine on adverse events following traumatic nasal surgeries is clinically significant. Clarifying their roles in reducing postoperative nausea, vomiting, shivering, hypotension, and bradycardia supports evidence-based anesthetic selection. This research enhances perioperative care by informing tailored anesthetic strategies, ultimately promoting patient safety, improving postoperative recovery, and optimizing outcomes in trauma patients undergoing nasal surgery.Material and methods: This prospective, randomized, double-blind clinical trial will compare ketamine and dexmedetomidine regarding adverse event incidence in adults undergoing traumatic nasal surgery. Consecutive eligible patients will be randomized and both participants and clinical staff will be blinded. Data on postoperative complications will be systematically collected and statistically analyzed. The study is ethically approved and complies with the Declaration of Helsinki, ensuring rigorous methodology, patient safety, and reliable, generalizable results for evidence-based anesthetic management.Results: The comparative analysis of ketamine and dexmedetomidine in patients undergoing traumatic nasal surgery revealed no significant differences in the incidence of postoperative adverse events, including nausea, vomiting, shivering, hypotension, and bradycardia requiring treatment. Both anesthetic agents demonstrated similar safety profiles, with low rates of hemodynamic complications and comparable risks for common postoperative events, supporting their use as equally viable options in this clinical context.Conclusion: This study demonstrates that ketamine and dexmedetomidine provide comparable safety profiles for patients undergoing traumatic nasal surgery, with no significant difference in the incidence of nausea, vomiting, shivering, hypotension, or bradycardia requiring intervention.

کلیدواژه ها:

Ketamine ، dexmedetomidine ، Postoperative complications ، Traumatic nasal surgery