The Relationship of Depression with Treatment Adherence in Patients with Multiple Sclerosis (MS): The Moderating Role of Sleep Quality

Objective: This research was conducted to study the role of sleep quality moderators in the relationship between depression and treatment compliance. Method: The research design was descriptive and correlational, and the research population included all patients with multiple sclerosis living in Tehran. ۲۲۹ subjects with Multiple Sclerosis were selected in a convenient method, and they were asked to answer Morinsky's treatment compliance, Petersburg sleep quality, and Beck's depression questionnaires using the pencil and paper method.Results: Evidence of the predictive role of depressive symptoms for poor adherence to treatment in patients with multiple sclerosis was found. In addition, evidence of the predictive role of sleep quality in treatment adherence was found, but its mediating role in the relationship between depression and treatment adherence was not found.Conclusion: The findings indicated the importance of depression symptoms and sleep quality in the treatment compliance of multiple sclerosis patients. Considering the importance of treatment compliance in the prognosis of the disease, it is suggested that doctors consider this issue to formulate treatment plans to target cognitive and emotional problems parallel to the main treatment of the disease and thereby increase treatment compliance.

کلیدواژه ها:

treatment compliance ، Depression ، Multiple Sclerosis ، Sleep quality