Application of artificial intelligence in the prevention and early diagnosis of cognitive decline in the aged: A Systematic Review

Background and Aims: Alzheimer’s disease (AD), which accounts for approximately ۷۰% of dementia cases, reduces quality of life and increases the cost of care. Early detection and intervention are crucial to slow the progression of the disease, but traditional methods such as cognitive tests and neuroimaging have limitations such as high costs and invasiveness. As a result, the need for accurate and affordable diagnostic tools has increased. Meanwhile, artificial intelligence (AI) has been proposed as a transformative technology in the diagnosis and prevention of cognitive decline. This systematically investigate the role of AI in the prevention and early diagnosis of dementia in the elderly, analyzing recent advances. Methods: This study was conducted in accordance with the PICO criteria, in line with the research objective, and guided by the PRISMA checklist. A comprehensive search of articles from ۲۰۱۹ to ۲۰۲۵ was conducted in the databases PubMed, SCOPUS, CINAHL, Web of Science, SID, and Magiran, as well as the Google Scholar search engine. The search was conducted using the MESH keywords 'artificial intelligence' 'early diagnosis' 'cognitive decline' 'aged' and using Boolean operators. Subsequently, two researchers independently reviewed and screened the retrieved articles based on the inclusion criteria. Results: review of the inclusion and exclusion criteria and assessment of the quality of the articles, ۸ articles out of a total of ۳۱۵ articles were included in the initial search. The findings indicate that artificial intelligence-based techniques, especially deep learning and machine learning, play an important role in the analysis of neuroimaging data and language and behavioral patterns for the early diagnosis of AD. In addition, the use of multimodal

کلیدواژه ها:

artificial intelligence ، early diagnosis ، cognitive decline ، aged