Synthesis and Characterization of γ-Fe۲O۳@HAp@β-CD Core-Shell Nanoparticles as a Novel Magnetic Nanoreactor and Its Application in the One-Pot Preparation of β-azido Alcohols, β-nitro Alcohols, and β-cyanohydrins

In this study, β-cyclodextrin(β-CD) supported, hydroxyapatite encapsulated γ-Fe۲O۳ (γ-Fe۲O۳@HAp@β-CD) was successfully prepared and evaluated as a solid-liquid phase transfer catalyst and also a molecular host system and nanoreactor for the nucleophilic ring-opening of epoxides in water for the preparation of β-azido alcohols, β-nitro alcohols, and β-cyanohydrins. The catalyst was characterized by FT-IR, XRD, TGA, and SEM. This procedure offers several advantages including excellent regioselectivity, high yields, short reaction times, recyclable catalyst, easy separation of the catalyst through external magnet, and easy work-up.

کلیدواژه ها:

Hydroxyapatite-encapsulated-γ-Fe۲O۳ ، β-Cyclodextrin ، epoxides ، β-azido alcohols ، β-nitro alcohols ، β-cyanohydrins