Effect of Parameters on Fiber Diameters and the Morphology of Hybrid Electrospun Cellulose Acetate/Chitosan/Poly(Ethylene Oxide) Nanofibers

Electrospun NanoFibers (ENFs) were fabricated from the mixture of Cellulose Acetate (CA), chitosan (CHI), and poly (ethylene oxide) using an acetic acid solution. The impact of CA/CHI ratio (۰.۵, ۱, ۱.۵ wt %), CHI/PEO ratio (۱, ۱.۵, ۲ wt%), Sodium Dodecyl Sulfate (SDS) (۰, ۱.۵, ۳% w/w) and ammonium oxalate (۳%, w/w) on the diameter, tensile strength, elongation, and porosity of the ENFs were optimized using Response Surface Methodology-Central Composite Rotatable Design (RSM-CCRD). The results revealed that ENFs were formed of non-woven fibers with a maximum diameter of ۱۱۳ nm. Second-order polynomial models with high R۲ values (۰.۹۹۶–۰.۹۹) were developed using Cubic analysis. The optimum condition was identified to be at the compounded level of CA/CHI ۱.۵ wt%, CHI/PEO ۱ wt%, and SDS ۳% (w/v). At the best point, the diameter, surface tension, elongation, and porosity of the fabricated ENFs were ۹۶.۰۷ nm, ۰.۰۵۴ N/mm۲, ۱۳.۰۹ mm, and ۵۲.۲۹ respectively.

کلیدواژه ها:

Electrospinning ، cellulose acetate ، Chitosan ، Fiber diameter ، Morphology