Phototherapy Technologies and Nanostructured Dressings for the Treatment of Infected Wounds

Introduction: Wound infections are a major problem in clinical practice because they can cause tissue damage, delayed healing, and even systemic infections. Antibiotics and other traditional treatment methods are losing their effectiveness, so researchers are looking into alternative therapies like phototherapy and nanostructured wound dressings. Phototherapy, which includes photodynamic therapy (PDT) and photothermal therapy (PTT), uses light energy to destroy microbes without damaging healthy tissue. Nanostructured dressings improve wound healing by acting as an antimicrobial, stimulating tissue regeneration, and delivering therapeutic agents. Material and Methods: This brief review paper demonstrates how nanostructured dressings and phototherapy technology can effectively heal infected wounds. Results and Discussion: There is great hope for the treatment of infected wounds with the combination of phototherapy and nanostructured dressings. When dressings containing silver nanoparticles were applied in conjunction with photodynamic treatment, the antibacterial activity against germs that were resistant to several drugs was significantly increased. Reducing bacterial load and stimulating tissue regeneration were both achieved using photothermal therapy with hydrogel dressings loaded with gold nanoparticles. To top it all off, the nanostructured dressings enhanced moisture retention and allowed for the regulated release of therapeutic chemicals, making for an ideal wound healing environment. Ensuring the nanomaterials' stability and safety over the long term and improving phototherapy dosage and light exposure are also ongoing challenges. Conclusion: An innovative and efficient method for treating infected wounds is the combination of phototherapy technology with nanostructured dressings. Wound healing outcomes can be improved with the help of these therapies, which not only fight antibiotic resistance but also promote tissue regeneration and increase the effectiveness of antimicrobials. Optimization of treatment procedures and assurance of biocompatibility should be the primary goals of future research into the practical application of these technologies in combination. Patients suffering from chronic and infected wounds may find new hope in the potential for these advanced therapies to be widely used in wound care in the future.

کلیدواژه ها:

Photothermal therapy ، wound healing ، Nanomaterials