Patients with COVID-۱۹: Predictors of Hospitalization in the Intensive Care Unit

Background: Identification of hospitalization predictors in patients with COVID-۱۹ is a key component in providing a quicker and more precise diagnosis and the patient’s priority for hospitalization. Objectives: The aim of this study was to determine the predictors of hospitalization in the intensive care unit (ICU) in patients with COVID-۱۹. Method: This research is a retrospective descriptive-analytical study and the data were obtained from the medical records of ۳۸۶ patients with confirmed COVID-۱۹ at Razi hospital in Rasht, North of Iran. Data were collected using a researcher-made questionnaire, including four sections of individual, clinical, laboratory, and respiratory factors of the patients. Data was analyzed using multiple logistic regression model in SPSS version ۱۶. Results: The rate of ICU hospitalization based on symptoms of shortness of breath (P<۰.۰۰۱), fatigue (P=۰.۰۱۵), loss of sense of smell (P=۰.۰۲۴), and other symptoms (P<۰.۰۰۱), taking anti-asthma and pulmonary drugs (P=۰.۰۰۶), and a history of smoking (P=۰.۰۰۲) was statistically significant. The mean and median scores of respiration rate (RR) (P<۰.۰۰۱), peripheral blood oxygen saturation (P<۰.۰۰۱), arterial oxygen relative pressure ratio to inspiratory oxygen fraction (P<۰.۰۰۱), blood pH (P=۰.۰۱۵), arterial blood oxygen pressure (P<۰.۰۰۱), and arterial blood oxygen saturation (P<۰.۰۰۱) showed a significant difference between the two groups of patients with and without ICU hospitalization. In the final logistic regression model, fever (odds ratio (OR)=۴, P=۰.۰۰۵), a history of smoking (OR =۶.۵, P=۰.۰۰۲), RR (OR=۱.۲, P=۰.۰۰۴), and arterial oxygen relative pressure ratio to inspiratory oxygen fraction (OR=۰.۹۷۴, P<۰.۰۰۱) were the most important predictors related to ICU hospitalization in patients with COVID-۱۹. Conclusion: The study results showed that identifying factors such as fever, a history of smoking, RR, and arterial oxygen relative pressure ratio to inspiratory oxygen fraction can help formulate prevention, treatment, and support plans for patients with COVID-۱۹.

کلیدواژه ها:

Coronavirus disease ۲۰۱۹ ، Intensive care unit ، Patient